Louisville Slugger Museum And Factory
This place is a shrine to the best known bat company in the world.  Walk through the factory while bats are being custom made for players in the pros.  The museum has game used bats from Babe Ruth to A-Rod, many you can hold yourself.  After the tour you get your very own souvenier sized bat, but if you're flying make sure you check it or the TSA will take it before you board.
Slugger Museum
Science Center Louisville Science Center
Our awesome Science museum is great for kids and adults.  It has all the typical children's museum stuff like putting yourself in a bubble, but it also has some cool original exhibits.  They have one exhibit which houses a human fetus in every stage of development, with explanations of the biological processes occuring. There's also a heart rate monitor which showed that Caitlan's heart sped up 5 BPM when Kyle was in the same room as her.
Muhammad Ali Center
Muhammad Ali is the most recognized sportsman in human history.  He is a driven fighter and, conversely, a driven peace advocate.  This center was founded not only to share his story and house many of his posessions but to promote peace and diversity in the Louisville area and beyond.  The Center hosts the Muhammad Ali Institute for Peace and Justice in partnership with the University of Louisville which advances the work, study and practice of peacemaking, social justice and violence prevention. It's also a pretty rocking museum.
Muhammad Ali
Bourbon Trail Kentucky Bourbon Trail
One third of all bourbon whiskeey comes from Louisville, the rest is within driving distance.  If the weather isn't nasty and you have some time on your drive in, stop by one or two of the distilleries that border Jefferson County. There's something magical that happens when the Kentucky limestone water mixes with the sour mash, it creates flavors unlike anywhere else in the world.
City
Accomodations Church